Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming.




Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming by Jie Deng et. al. published in Nature Biotechnology 27, 353 – 360 (2009). Abstract Current DNA methylation assays are limited in the flexibility and efficiency of characterizing a large number of genomic targets. We report a method to specifically capture an arbitrary […]






Analysing and interpreting DNA methylation data




Analysing and interpreting DNA methylation data by Christoph Bock published in Nature Review Genetics, October 2012. Abstract DNA methylation is an epigenetic mark that has suspected regulatory roles in a broad range of biological processes and diseases. The technology is now available for studying DNA methylation genome-wide, at a high resolution and in a large […]