Chromatin accessibility pre-determines glucocorticoid receptor binding patterns




Chromatin accessibility pre-determines glucocorticoid receptor binding patterns by Sam John et. al. published in Nature Genetics 43, 264–268 (2011). Abstract Development, differentiation and response to environmental stimuli are characterized by sequential changes in cellular state initiated by the de novo binding of regulated transcriptional factors to their cognate genomic sites1, 2, 3. The mechanism whereby […]