Genotype calling and phasing using next-generation sequencing reads and a haplotype scaffold




Genotype calling and phasing using next-generation sequencing reads and a haplotype scaffold Androniki Menelaou and Jonathan Marchini published in Bioinformatics October 2012. Abstract Motivation: Given the current costs of next generation, sequencing large studies carry out low-coverage sequencing followed by application of methods that leverage linkage disequilibrium to infer genotypes. We propose a novel method […]






Next-generation sequencing data interpretation: enhancing reproducibility and accessibility




Next-generation sequencing data interpretation: enhancing reproducibility and accessibility by Anton Nekrutenko & James Taylor published in Nature Review Genetics, September 2012. Abstract Areas of life sciences research that were previously distant from each other in ideology, analysis practices and toolkits, such as microbial ecology and personalized medicine, have all embraced techniques that rely on next-generation […]